University of California San Francisco

KIR Genotyping

Test

KIR genotyping

Purpose

  • To select stem cell donors to improve leukemia control after hematopoietic stem cell transplantation
  • To determine disease association

Highlights

  • ITL reports KIR genotyping results as positive or negative for the following KIR genes and common variants: 2DL1, 2DL2, 2DL3, 2DL4, 2DL5A, 2DL5B, 2DS1, 2DS2, 2DS3, 2DS4*FUL, 2DS4*DEL, 2DS5, 3DL1, 3DL2, 3DL3, 3DS1, 2DP1, and 3DP1.
  • In addition to reporting results as Positive or Negative for KIR genes and their common variants, the report also lists the number of activating KIR genes, AA/AB/BB KIR haplotype composition, centromeric and telomeric gene constellations, and predicted ligands from the available HLA Class I typing. 
  • Consultation is available for donor selection and interpretation of results. 

Turn-Around-Time

  (assuming samples received before 10:00 am)

  • Routine test results in 2-4 business days
  • STAT testing in ≤ 3 business days