Disease Association and Drug Hypersensitivity

Tests

• HLA-B27 is associated with a group of autoimmune diseases termed seronegative spondyloarthropathies, which included ankylosing spondylitis, psoriatic arthritis, and reactive arthritis (formerly termed Reiter syndrome). 
• HLA-A29 is associated with Birdshot Retinochoroidopathy
• HLA-B51 is associated with Behcet’s disease, a rare chronic inflammatory multisystem disorder. 
• HLA-B*15:02 is strongly associated with hypersensitivity to carbamazepine, an anti-epileptic medication.
• HLA-B*57:01 is strongly associated with hypersensitivity to abacavir, a retroviral medication.
• HLA-B*58:01 is strongly associated with hypersensitivity to allopurinol, a medication used for hyperuricemia-related diseases such as gout and recurrent urate kidney stones.
• HLA-DQ2 and HLA-DQ8 are associated with risk of Celiac disease.

Highlights  

• Tested at the optimum resolution.
• Test comments that are relevant to clinical management are included in the report.
• Consultation is available for test selection and interpretation of results.

• Routine testing reported in 4-10 business days
• STAT testing reported in ≤ 3 business days