Immunogenetics and Transplantation Laboratory (ITL) - Homepage
The UCSF Immunogenetics and Transplantation Laboratory (ITL)
Ultra high-resolution HLA typing by Next-Generation Sequencing technologies
State-of-the-art histocompatibility and Immunogenetics diagnostics
High-throughput HLA antibody screening with minimal MFI variation
Real-time PCR approach for rapid HLA typing
The Immunogenetics and Transplantation Laboratory provides quality diagnostic testing, research, and education as vital contributions to optimal patient care and leadership in the advancement of our discipline.
Rajalingam Raja
Director, Immunogenetics & Transplantation Lab
Collaborations
Our Research
- Define the functional histocompatibility to increase the number of transplants and improve transplant outcomes by identifying acceptable HLA mismatches and tolerable donor-specific HLA antibodies (DSA)...
- Understand the function of germline-encoded polymorphism of immunity related genes (HLA, KIR, KLR, and FcR) in human populations and their impact on infections, tumor transformation, autoimmune diseases, pregnancy success and allogeneic solid organ and bone marrow transplantation....
- Genes encoding killer-cell Immunoglobulin-like receptors (KIR) and HLA class I ligands are located on different chromosomes, and both feature extraordinary diversity in the number and type of genes...
Support the Lab
Your generous support of the Immunogenetics and Transplantation Laboratory helps scientists discover new treatments for bone marrow, cornea transplantation and more.